Advances in point-of-care testing for new corona virus nucleic acid
10.11665/j.issn.1000-5048.20200601
- VernacularTitle:用于新型冠状病毒核酸检测的即时检测方法研究进展
- Author:
Yaofei BAO
1
;
Qianru XUE
;
Haiping WU
;
Bingjie ZOU
;
Qinxin SONG
;
Guohua ZHOU
Author Information
1. 中国药科大学药物质量与安全预警教育部重点实验室
- Publication Type:Journal Article
- Keywords:
SARS-CoV-2;
nucleic acid detection;
point-of-care testing;
advances
- From:
Journal of China Pharmaceutical University
2020;51(6):635-645
- CountryChina
- Language:Chinese
-
Abstract:
The corona virus disease 2019 (COVID-19) caused by the new coronavirus (SARS-CoV-2) has spread rapidly around the world,posing a serious threat to the public"s health. As of September 30,2020,the number of infected people in the world has reached 33 million,causing more than 1 million deaths. Normalized nucleic acid detection methods based on lab have long turnaround time and high cost. Therefore,there is an urgent need to develop a convenient method to detect SARS-CoV-2,so as to achieve rapid testing and timely control of the epidemic when resources are limited.This review summarizes the point-of-care testing (POCT) methods developed for SARS-CoV-2 in terms of extraction,amplification and detection,and briefly introduces commercial POCT instruments that integrate these three steps,in order to provide references for emergency response and rapid deployment of COVID-19 and other emerging infectious diseases.
