Quality of Life in Patients with Parkinson's Disease.
- Author:
Seuk Kyung HONG
1
;
Kyung Won PARK
;
Jae Kwan CHA
;
Sang Ho KIM
;
Dong Yeol CHUN
;
Chang Kook YANG
;
Jae Woo KIM
Author Information
1. Department of Neurology, College of Medicine, Dong-A University, Korea. jwkim@mail.donga.ac.kr
- Publication Type:Original Article
- Keywords:
Parkinson's disease;
Quality of life;
Parkinson's disease quality of life questionnaire;
Depression
- MeSH:
Activities of Daily Living;
Age of Onset;
Anxiety;
Chronic Disease;
Cognition;
Depression;
England;
Humans;
Hypokinesia;
Motor Activity;
Neurodegenerative Diseases;
Parkinson Disease*;
Psychology;
Quality of Life*;
Surveys and Questionnaires
- From:Journal of the Korean Neurological Association
2002;20(3):227-233
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Quality of life (QoL) has emerged as an important issue to patients with chronic illness. Parkinson's disease (PD) is a chronic neurodegenerative disorder requiring life-time treatment and supportive care, which affects not only physical activity but also cognition, mood, and daily living. The author investigated the QoL of patients with PD and aimed to find factors that have an influence on the QoL. METHODS: One hundred thirty patients with PD were evaluated. The QoL was measured and assessed by the Parkinson's disease quality of life questionnaire (PDQL). The author analyzed demographic and social data and clinical profiles. The Beck Depression Inventory (BDI) and Spielburger's State-Trait Anxiety Inventory were used to evaluate depressive symptoms and anxiety levels. RESULTS: The mean age of onset of parkinsonian symptom was 55.2 +/-10.9 years and the average duration of treatment was 34.7 +/-36.9 months. Patients with high BDI score, low Schwab and England activities of daily living scale (SEADLS) score, high bradykinesia score, progressed Hoehn and Yahr stage, high Unified Parkinson's disease rating scale score, low educational period and high economic state were all correlated with low PDQL scores. Multivariate regression analysis showed that BDI score, bradykinesia score, SEADLS score, and educational period were significantly associated with PDQL score. CONCLUSIONS: In order of magnitude, BDI, bradykinesia, SEADLS and educational period were influenc-ing factors on PDQL. Therefore, to improve the QoL in patients with PD, we should consider not only physical disabili-ty, but also psychological factors, including depressive mood.