The Efficacy of the Alpha-Blocker, Tamsulosin, in the Patients with Benign Prostatic Hyperplasia of 30 grams or less.
- Author:
Sang Hoon LEE
1
;
Woo Sik CHUNG
;
Bong Suk SHIM
Author Information
1. Department of Urology, College of Medicine, Ewha Womans University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Benign prostatic hyperplasia;
Adrenergic alpha-antagonists
- MeSH:
Adrenergic alpha-Antagonists;
Humans;
Prostate;
Prostatic Hyperplasia*
- From:Korean Journal of Urology
2004;45(5):428-432
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Medical therapy with an alpha-blocker is commonly used primarily in patients with benign prostatic hyperplasia (BPH). However, the efficacy of the alpha-blocker is still questionable in reference to a small prostate, with the size of 30g or less. We reviewed 117 patients who had been taken the alpha-blocker for the management of BPH, and the results were analyzed according to the prostatic size. MATERIALS AND METHODS: One hundred seventeen patients were divided into the two following groups: Group I consisted of 57 patients with a BPH of under 30g and Group II consisted of 60 patients with a BPH of over 30g. Both groups were evaluated for the international prostate symptom score, urine flow rate, and residual urine volume before and 3 months after receiving medical therapy with tamsulosin. RESULTS: The success rate after medical therapy was similar in both groups, and all components were significantly improved after 3 months. The improvement rate of the urine flow rate was more significant in group II than group I. CONCLUSIONS: According to several objective results and the preference of patients for this treatment, medical therapy with the alpha-blocker could be also available in patients with BPH of under 30g.
