A new cucurbitane triterpene in acid-treated ethanol extract from Momordica charantia
10.3969/j.issn.1674-6348.2013.03.009
- Author:
Jia-qing CAO
1
Author Information
1. School of Traditional Chinese Materia Madica
- Publication Type:Journal Article
- Keywords:
5β,19-epoxy-cucurbita-6,22(E),24-trien-3β-ol;
Cucurbitane;
Hydrolysate;
Momordica charantia;
Triterpene
- From:
Chinese Herbal Medicines
2014;5(3):234-236
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents in the acid-hydrolyzed ethanol extract from Momordica charantia. Methods: The ethanol extract from M. charantia was hydrolyzed by 36% HCl and the hydrolysate was isolated by silica gel column chromatography and preparative HPLC. The structures of the isolated compounds were identified by spectral analyses, physical constants, and chemical evidences. Results: Two cucurbitane triterpenoids were isolated and identified as 5β,19-epoxy-cucurbita-6,22. E,24-trien-3β-ol (1) and cucurbita-6,22(E),24-trien-3β-ol-19,5β-olide (2). Conclusion: Compound 1 is a new compound. © 2013 Tianjin Press of Chinese Herbal Medicines.
