A New Hasubanan Alkaloid from Stephania hernandifolia
10.1016/S1674-6384(14)60010-1
- Author:
Lu-lu DENG
1
Author Information
1. School of Chemistry and Material Science
- Publication Type:Journal Article
- Keywords:
Cytotoxicity;
Hasubanan alkaloid;
Hernsubanine D;
Menispermaceae;
Stephania hernandifolia
- From:
Chinese Herbal Medicines
2015;6(1):70-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of Stephania hernandifolia. Methods: Various chromatographic techniques were used to isolate the constituents, and the structures were elucidated on the basis of HR-EI-MS, 1D-NMR and 2D-NMR spectral analyses. Results: A hasubanan alkaloid, hernsubanine D (1) was isolated from the whole plants of S. hernandifolia. The compound was screened for the cytotoxic activity against two human cancer cell lines in vitro. Conclusion: Compound 1 is a new compound without cytotoxicity against A549 and K562 cells. © 2014 Tianjin Press of Chinese Herbal Medicines.
