Comparison on Traditional and Machinery Decoctions for Da-cheng-qi Decoction Based on Chemical Ingredients, Pharmacological Functions, and Clinical Trials
10.1016/S1674-6384(15)60064-8
- Author:
Rui-Fang XIE
1
Author Information
1. Department of Pharmacy, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medcine
- Publication Type:Journal Article
- Keywords:
Chemical ingredients;
Clinical trials;
Da-cheng-qi Decoction;
Machinery decoction under high pressure;
Machinery decoction under normal pressure;
Pharmacological functions;
Traditional decoction
- From:
Chinese Herbal Medicines
2015;7(4):354-364
- CountryChina
- Language:Chinese
-
Abstract:
Objective: Patients and doctors often have questions about the equivalence of traditional and machinery decoctions. In this article, using Da-cheng-qi Decoction (DCQD) as a model of formula, traditional decoction (TD), machinery decoction under high pressure (MDHP), and machinery decoction under normal pressure (MDNP) were compared. Methods: For chemical components, HPLC fingerprints were established and evaluated using AHP combined with CRITIC weighing method; For animals' effects, the experiments of small intestinal propulsion were conducted; For clinical effects, a randomized clinical trial (RCT) was designed and performed. Results: Although there were some differences between TD and MDNP in chemical ingredients, there was no significant difference in animal experiments and clinical trials (P > 0.05). Conclusion: The traditional and machinery decoctions of DCQD could be used bioequivalently.
