A new coumarin glucoside ester from seeds oil leavings of Xanthoceras sorbifolia
10.1016/j.chmed.2018.09.003
- Author:
Hong-jin ZHU
1
Author Information
1. College of Basic Science, Jinzhou Medical University
- Publication Type:Journal Article
- Keywords:
coumarin;
cytotoxicity;
fraxetin;
fraxoside;
Xanthoceras sorbifolia Bunge
- From:
Chinese Herbal Medicines
2019;11(1):113-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the coumarin from the seeds oil leavings of Xanthoceras sorbifolia. Methods: The chemical constituents were isolated and purified by combination of silica gel, macroporous resin, Sephadex LH-20, and ODS column chromatography. Their structures were elucidated by spectral and chemical methods. The cytotoxicity of the new compound against 10 selected human cancer cell lines was assayed. Results: Five comarins were isolated and identified as fraxetin-7-O-β-D-[6’-(3’'‑hydroxyl‑3’’- methylglutaryl)] glucopyranoside (1), fraxoside (2), fraxetin (3), scopoline (4), and esculetin (5), respectively. Conclusion: Compound 1 is a new compound. Unfortunately, this compound exhibited no cytotoxicity with tested cell lines.
