Effects of hyperbaric oxygen preconditioning on physical stamina in mice
- Author:
Zhao-Yun PENG
1
Author Information
1. Department of Nautical Medicine
- Publication Type:Journal Article
- From:
Academic Journal of Second Military Medical University
2006;27(1):62-64
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of hyperbaric oxygen (HBO) on the physical stamina in mice. Methods: Sixty Kunming mice were randomly assigned into 3 groups: HBO group, high pressure air (HPA) group, and normal pressure air (NPA) group. After 5 days' exposure, 30 mice (10 in each group) were subjected to forced swimming test (FST) to measure the exhaustive swimming time. Blood lactate (LA), malondialdehyde (MDA) and superoxide dismutase (SOD) were measured in another 10 mice after 90 min swimming. Results: Compared to HPA group, HBO group had obviously longer exhaustive swimming time (P<0.05). The blood LA in HBO group was lower than that in HPA group and NPA group after 90 min swimming (P<0.05); there was no significant difference in SOD activity and MDA content between 3 groups. Conclusion: HBO can markedly improve the physical stamina in mice, which may not be related with the activity of anti-oxidation enzyme and metabolism of oxygen free radical.
