Damage of mitochondrial DNA and its influence on cells
- Author:
Chun TANG
1
Author Information
1. Southwest Hospital
- Publication Type:Journal Article
- From:
Academic Journal of Second Military Medical University
2006;27(2):211-214
- CountryChina
- Language:Chinese
-
Abstract:
Mitochondrial DNA(mtDNA), a double-stranded circular molecular, encodes several genes essential for mitochondrial and cellular functions despite its small amount of genetic information. Damage of mtDNA can lead to changes of cellular structures and functions and this fact is drawing more and more attention. This review summarized the recent research about mtDNA damage and its influence on cells.