Retroperitoneal laparoscopic nephrectomy and open nephrectomy for radical treatment of renal cell carcinoma: A comparison of clinical outcomes
- Author:
Bo PENG
1
Author Information
1. Department of Urology
- Publication Type:Journal Article
- From:
Academic Journal of Second Military Medical University
2006;27(11):1167-1169
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare the clinical outcomes of laparoscopic nephrectomy and open nephrectomy for radical treatment of renal cancer. Methods: Fifty-three patients with renal cell carcinoma (due to receive radical renal tumor resection) were randomly allocated into 2 groups: retroperitoneal laparocopic (RL) group (n = 27) and open approach (OA) group (n = 26). The operation time, hospital stay, use of painkiller, fasting period after operation, and blood loss during operation were analyzed and compared. All the cases were followed up for 6-12 months and the survival rates, wound healing, and carcinoma metastasis were recorded. Results: Patients in both groups were all successfully treated and their sexes, clinical stages, ages, and tumor sizes were all comparable. The operation time was similar in the 2 groups, with that of RL group being (66.66±10.37) min and of OA group being (69.08±11.22) min. The fasting period in RL group ([1±0.36] d) was significantly shorter than that in the OA group ([2±0.68] d, P<0.05). The hospital stay in RL group (6.92±0.96) was significantly shorter than that in OA group (11.42±1.57, P<0.05). The blood loss in RL group ([72.03±19.37] ml) was less than that in OA group ([154.4±20.42] ml, P<0.01). The use of painkiller was 2 person-times in the RL group and 20 person-times in the OA group (P<0.01). No post-operation infection was noticed in RL group and there was one case of infection in OA group during follow-up. Conclusion: Compared with traditional open radical nephrectomy, laparoscopic radical nephrectomy has the advantages of rapid recovery, less pain, less blood loss, and less complications, etc.
