Peroxisome proliferator-activated receptor-alpha and diabetic nephropathy
- Author:
Jie-Li HUANG
1
Author Information
1. Department of Nephrology
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathies;
PPAR gamma;
Thiazolidinediones
- From:
Academic Journal of Second Military Medical University
2010;27(12):1372-1374
- CountryChina
- Language:Chinese
-
Abstract:
Peroxisome proliferator-activated receptor (PPAR), a member of nuclear hormone receptor superfamily, has 3 subtypes, namely, PPARα, PPARβ/δ, and PPARγ; among them PPARγ plays an important role in adipogenesis, lipid metabolism, insulin sensitivity, inflammation, atherosclerosis, and blood pressure controlling. This article reviews the relationship between PPARγ and diabetec nephropathy.
