Cognitive disorders in patients with obstructive sleep apnea hypopnea syndrome: A review of literature
- Author:
Peng ZHANG
1
Author Information
1. Department of Neurology
- Publication Type:Journal Article
- Keywords:
Cognition disorders;
Hypoventilation;
Obstructive;
Sleep apnea
- From:
Academic Journal of Second Military Medical University
2010;28(4):434-437
- CountryChina
- Language:Chinese
-
Abstract:
Patients possibly incur cognitive disorders when they suffer from obstructive sleep apnea hypopnea syndrome (OSAHS). The pathogenesis of OSAHS is mainly associated with turbulence of sleep structure and chronic episodic hypoxia during sleep, and the pathological changes in cerebral areas hypersensitive to hypopnea may be responsible for cognitive dysfunction. It has been preliminarily showed that cognitive disorder in OSAHS is a generalized cognitive impairment and is possibly associated with Alzheimer's disease (AD). Recently, measures for cognitive evaluation have been improved by the application of the neuroimage: however,to build a highly specific, maneuverable evaluation system still demands more exertion. Despite the fact that early remedies for OSAHS may slow down the cognitive dysfunction,there still lacks specialized treatment for cognitive disorders. OSAHS is not rare in children and it can affect their cognitive function, which demands more attention.
