Noise-induced hearing loss and cochlea neurotransmitters: Recent progress
- Author:
Yan-Min ZHANG
1
Author Information
1. Department of Physiology
- Publication Type:Journal Article
- Keywords:
Adenosine triphosphate;
Cochlea;
Dopamine;
Gamma-aminobutyric acid;
Glutamateic acid;
Hearing loss;
Noise-induced;
Spiral ganglion
- From:
Academic Journal of Second Military Medical University
2010;28(4):430-433
- CountryChina
- Language:Chinese
-
Abstract:
Being the primary neurons in the auditory system, spiral ganglion neurons form the afferent synapse with hair cells and play a critical role in the analysis and integration of hearing. Many kinds of neurotransmitters can be found in the cochlear and they have different effects under both physiological and pathological conditions with complicated mechanism. This article reviews the characters of some transmitters in cochlear, such as glutamate, ATP, dopamine and GABA, and their roles in noise-induced hearing loss, hoping to provide more clues for research and therapy of inner ear diseases.