Drug and protein interactions: Progress of research methods
- Author:
Hong JIANG
1
Author Information
1. Department of Analytical Chemistry
- Publication Type:Journal Article
- Keywords:
Drugs;
Interaction;
Protiens
- From:
Academic Journal of Second Military Medical University
2010;28(6):662-666
- CountryChina
- Language:Chinese
-
Abstract:
Interaction between drug and protein is a major research field of life science. This article reviews the methods used in related research in the past 5 years, including spectroscopy, equilibrium dialysis, ultrafiltration, microdialysis method, capillary electrophoresis, NMR, X-ray diffraction, electrochemical, affinity chromatography, HPFA, HPLC, etc. It has been showed that combined usages of several technologies are always needed to elucidate an interaction between drug and protein.
