A Case of Postpregnancy Spinal Osteoporosis.
- Author:
Ji Young SEO
1
;
Hyeon Kyu KIM
;
Cheol Soo CHOI
;
Doo Man KIM
;
Sung Hee LIM
;
Jae Myung YOO
;
Moon Gi CHOI
;
Huung Joon YOO
;
Sung Woo PARK
;
Jin Young LEE
Author Information
1. Department of Internal Medicine, Hallym University,College of Medicine, Chuncheon, Korea.
- Publication Type:Case Report
- Keywords:
Pregnancy-associated osteoporosis;
Fracture;
PTHRP
- MeSH:
Aged;
Back Pain;
Bone Resorption;
Female;
Fractures, Compression;
Hip;
Humans;
Osteoporosis*;
Parathyroid Hormone-Related Protein;
Pregnancy;
Skeleton;
Spine
- From:Journal of Korean Society of Endocrinology
2001;16(2):265-270
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Osteoporosis is a common disease of the elderly and occurs especially in the postmenopausal women. Rarely, it occurs during a pregnancy or shortly thereafter and is accompanied by a substantial bone loss, resulting in fractures. The clinical significance of pregnancy-associated osteoporosis has been noted since the 1950s. Although its etiology is still unknown, it has recently been proposed that PTHrP may be an important causative factor in pregnancy-associated osteoporosis. There are three types of the pregnancy-associated osteoporosis, (1) a transient osteoporosis of the hip pregnancy, (2) a postpregnancy spinal osteoporosis and (3) a lactation-associated osteoporosis. Postpregnancy spinal osteoporosis typically occurs within three months after a first delivery and usually involving the axial skeleton accompanied by back pain, bone loss and a fracture. We present a case of postpregnancy spinal osteoporosis that developed three months after a first delivery. Our patient also showed multiple compression fractures in her lumbar spine and biochemical evidence of increased bone resorption.
