S100A1 protein and heart failure
10.3724/SP.J.1008.2008.00331
- Author:
Ru-Yi XU
1
Author Information
1. Postgraduate College
- Publication Type:Journal Article
- Keywords:
Calcium;
Heart failure;
Myocardial contraction;
S100A1 protein
- From:
Academic Journal of Second Military Medical University
2010;29(3):331-333
- CountryChina
- Language:Chinese
-
Abstract:
S100A,a Ca2+-depending inotropic factor in the heart,is found decreased during hear failure. Increase of S100A1 protein expression can improve cardiac function by regulating Ca2+ transportation, inhibiting left ventricular remodeling, decreasing apoptosis,and restoring energy supply of failing heart. Therefore,recovery of S100A1 protein expression in the failing heart is an effective strategy for treatment of heart failure.
