Changes of serum TK1 level during chemotherapy of patients with non-Hodgkin's lymphoma and its significance
10.3724/SP.J.1008.2008.01384
- Author:
Zhu-Lin PAN
1
Author Information
1. Department of Hematology
- Publication Type:Journal Article
- Keywords:
Drug therapy;
Non-Hodgkin's lymphoma;
Thymidine kinase 1
- From:
Academic Journal of Second Military Medical University
2010;29(11):1384-1385
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To understand the significance of serum TK1 level change during chemotherapy of patients with non-Hodgkin's lymphoma. Methods: The serum TK1 levels were detected in 37 patients with non-Hodgkin's lymphoma by enhanced chemiluminecence assay before chemotherapy and one day, four weeks after chemotherapy. Results: The changes of serum TK1 levels were significantly different at different stages of treatment (P<0.01). Conclusion: Our findings indicate that serum TK1 change might be of great value in evaluating the treatment outcomes and predicting recurrence of patients with non-Hodgkin's lymphoma.