Application of ultrasmall superparamagnetic iron oxide in MRI diagnosis of central nervous system: Recent progress
10.3724/SP.J.1008.2008.01503
- Author:
Xiao-Long MA
1
Author Information
1. Department of Radiology
- Publication Type:Journal Article
- Keywords:
Atherosclerotic plaque;
Brain neoplasms;
Macrophage;
Magnetic resonance imaging;
Multiple sclerosis;
Ultrasmall superparamagnetic iron
- From:
Academic Journal of Second Military Medical University
2010;29(12):1503-1506
- CountryChina
- Language:Chinese
-
Abstract:
Ultrasmall superparamagnetic iron oxide (USPIO), as the contrast agent of MRI, possesses two major properties: long half time in the plasma and specific binding with macrophages. Compared with gadolinium, widely-used in clinic presently, USPIO has its unique advantages in diagnosis of central nervous system diseases, though which still need further clinical verification. This article reviews the application of USPIO in MRI diagnosis of some central nervous system diseases.