Clinical and coronary angiographic analysis of elderly patients with type 2 diabetes mellitus combined with coronary heart disease
10.3724/SP.J.1008.2009.00286
- Author:
Su-Xuan LIU
1
Author Information
1. Department of Cardiovasology
- Publication Type:Journal Article
- Keywords:
Aged;
Coronary angiograph;
Coronary disease;
Insulin resistance;
Type 2 diabetes mellitus
- From:
Academic Journal of Second Military Medical University
2010;30(3):286-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the association of type 2 diabetes mellitus (DM) with the clinical and coronary angiographic features of coronary heart disease (CHD) in patients aged over 70 years old. Methods: A total of 310 elderly patients with coronary angiograph-confirmed coronary diseases, who were treated in Changhai Hospital during Apr. 2006 to Jul. 2008, were retrospectively analyzed. The patients were further divided into 2 subgroups according to the presence of DM: DM-CHD group (n = 155) and non-DM-CHD group (n = 155). The age, gender, blood pressure, blood lipid, ejection fraction (EF), the angiographic outcomes, etc. were analyzed and compared between the two groups. Results: The incidence of hypertension was significantly higher in the DM-CHD group than in the non-DM-CHD group (P<0.05). The fasting blood glucose (FBG), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and fibrinogen (FIB) were significantly higher than those in the other group (P<0.01), and the high density lipoprotein cholesterol (HDL-C) was lower than that in the other group (P<0.05). The EF value in the DM-CHD group was significantly lower than that in the non-DM-CHD group (P< 0.01). Among the 35 (22%) patients preliminarily diagnosed as having DM, 14 (40%) would be misdiagnosed if the diagnosis depends solely on FBG without oral glucose tolerance test (OGTT). The prevalence of diffusive coronary lesions in the DM-CHD group was significantly higher than that in the non DM group (P<0.01). DM-CHD group also had significantly higher coronary stenosis index (P<0.01) and more occlusive vessels than non-DM-CHD group. Conclusion: The missed diagnosis rate of DM is high in CHD patients. Compared with non-DM-CHD patients, DM-CHD patients are at higher risks for coronary disease and have more severe coronary lesions.
