Cancer stem cells of multiple myeloma: Recent progress
10.3724/SP.J.1008.2009.00953
- Author:
Xiao-Qun YANG
1
Author Information
1. Department of Pathology
- Publication Type:Journal Article
- Keywords:
Memory B-lymphocytes;
Multiple myeloma;
Neoplastic stem cells;
Niche;
Side population
- From:
Academic Journal of Second Military Medical University
2010;30(8):953-955
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells (CSCs) are a small proportion of tumor cells with the property of stem cells in the tumor tissue; they are capable of self-renewal, multi-lineage differentiation and serve as the source of tumor cells and tumor tissues. The discovery of multiple myeloma CSCs and the study on its relationship with side population cells and niche provide a new interpretation on the pathogenesis of multiple myeloma.