Study on chemical constituents of methylene chloride extract of Rubus chingii
10.3724/SP.J.1008.2009.01199
- Author:
Meng-Tao YOU
1
Author Information
1. Department of Pharmacognosy
- Publication Type:Journal Article
- Keywords:
Chemical constituents;
Lignan;
Phenol;
Rubus chingii
- From:
Academic Journal of Second Military Medical University
2010;30(10):1199-1202
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the chemical constituents of the methylene chloride of Rubus chingii Hu.. Methods: Chromatography on silica gel column, Sephadex LH-20 column, and recrystallization technique were used to isolate and purify the compounds. Spectroscopy methods including EI-MS, ES-MS, 1H-NMR, 13CNMR, HMQC, and HMBC were used to elucidate the structures of compounds. Results: Ten compounds were obtained and 9 compounds were identified as: hexacosanol (I), β-sitosterol (II), 4-hydro-3-methlbenzal acid (III), 4-hydrobenzal dehyde (IV), oleanolic acid (V), stigmast-5-en-3-ol, oleate (VI), H-2-indenone, 2, 4, 5, 6, 7, 7a-hexahydro-3-(1-methylethyl)-7a-methyl (VIII), 4-hydroxy-3-methoxybenzoic acide (IX), and liballinol (X). Conclusion: Compounds I, III, IV, VI, VIII, and X have been obtained from Rubus chingii for the first time.
