Chemical constituent analysis of EtOAc fraction of Tithonia diversifolia (HEMSL.) A. Gray
10.3724/SP.J.1008.2010.00189
- Author:
Gui-Jun ZHAO
1
Author Information
1. Department of Pharmacognosy
- Publication Type:Journal Article
- Keywords:
Chemical constituents;
Ethyl acetate portion;
Tithonia diversifolia
- From:
Academic Journal of Second Military Medical University
2010;31(2):189-192
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To isolate and identify the chemical constituents of the EtOAc fraction of Tithonia diversifolia. Methods: The dried aerial parts of Tithonia diversifolia were extracted with 80% EtOH,and the chemical constituents of the ethyl acetate portion from the extract were isolated by column chromatography with silica gel, Sephadex LH-20 and MCI. The isolated compounds were identified by NMR and MS analysis. Results: Ten compounds were isolated from EtOAc extract, and identified as, vanillin (1), ergosterol (2), ergosterol peroxide (3), 3-methoxy-4-hydroxy-trans-cinnamaldehyde (4), 3-hydroxybenzaldehyde (5), 7-methylesculetin (6) , 5-hydyoxymethyl furfural (7), nepetin (8) , docosanoic acid 2, 3-dihydroxypropyl ester(9) and 13-hydroxyeupatorochromene(10). Conclusion: Vanillin, ergosterol, ergosterol peroxide, 3-methoxy-4-hydroxy- trans-cinnamaldehyde, p-hydroxybenzaldehyde, 7-methylesculetin, 5-hydyoxymethyl furfural, docosanoic acid 2, 3-dihydroxypropyl ester, and 13- hydroxyeupatorochromene have been isolated from Tithonia diversifolia for the first time.
