Mechanisms of obesity-related hypertension: Recent progress
10.3724/SP.J.1008.2010.00442
- Author:
Yi-Bin LUO
1
Author Information
1. Department of Endocrinology
- Publication Type:Journal Article
- Keywords:
Adiponectin;
Insulin;
Leptin;
Obesity-related hypertension;
Renin-angiotensin system
- From:
Academic Journal of Second Military Medical University
2010;31(4):442-444
- CountryChina
- Language:Chinese
-
Abstract:
Obesity is the most important risk factor of primary hypertension. Rapid increase of obesity-related hypertension has become a worldwide problem. But the specific mechanism of the condition remains to be fully understood. This paper reviews the latest literatures and tries to explain the mechanism of obesity-related hypertension from the following four aspects: hypoadiponectinemia, leptin and resistance of leptin, insulin and resistance of insulin and the activation of renin-angiotensin system(RAS).