Surgical treatment of obstructive jaundice induced by biliary invasion in patients with gallbladder cancer: An analysis of outcome in 48 cases
10.3724/SP.J.1008.2010.00857
- Author:
Fei-Ling FENG
1
Author Information
1. Department of Biliary Tract I
- Publication Type:Journal Article
- Keywords:
Biliary invasion;
Gallbladder neoplasms;
Obstructive jaundice;
Radical resection
- From:
Academic Journal of Second Military Medical University
2010;31(8):857-860
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze the outcomes of surgical treatment of obstructive jaundice induced by biliary invasion in patients with gallbladder carcinoma. Methods: We retrospectively analyzed the clinical data of 48 patients with gallbladder cancer and biliary invasion-induced obstructive jaundice, who were treated in our hospital during January 2004 to December 2008. Results: Thirty-six patients who received surgical treatment had a median survival time of (17.39±3.98) months, and 12 patients received non-surgical treatment had a median survival time (3.75±0.51) months, with significant difference found between the two groups (P<0.01). Fifteen patients underwent radical resection, 7 underwent R1 resection, and 14 underwent R2 resection, with their median survival time being (30.93±7.42) months, (13.57±6.70) months, and (5.00±0.67) months, respectively; there were significant difference between the three groups (P<0.01). Conclusion: The prognosis of gallbladder cancer with obstructive jaundice is poor; surgical treatment can partly improve the prognosis of patients with obstructive jaundice-induced by gallbladder invasion. Radical curative resection, sometime with cholecystectomy, partial hepatectomy, or bile duct resection, should be performed for these patients.
