Interferon-gamma and systemic lupus erythematosus
10.3724/SP.J.1008.2010.01020
- Author:
Jia XIA
1
Author Information
1. Department of Rheumatology
- Publication Type:Journal Article
- Keywords:
Interferon-γ;
Systemic lupus erythematosus;
Thl-type cytokine
- From:
Academic Journal of Second Military Medical University
2010;31(9):1020-1022
- CountryChina
- Language:Chinese
-
Abstract:
The etiology and pathogenesis of systemic lupus erythematosus(SLE) remain unclear. Interferon-γ (IFN-γ), a Th1-type cytokine, may be involved in the pathogenesis and inflammatory process of SLE. This article reviews reports on the serum IFN-γ of SLE patients and mouse SLE models, in vitro secreted IFN-γ, expression of IFN-γ induced protein and IFN-γ related genes, and treatment with traditional Chinese medicines.
