Roles of androgen receptor and Wnt signaling pathway in prostate cancer
10.3724/SP.J.1008.2010.01244
- Author:
Hai-Bo SHENG
1
Author Information
1. Department of Urology
- Publication Type:Journal Article
- Keywords:
Androgen receptors;
Prostatic neoplasms;
Wnt signaling pathway
- From:
Academic Journal of Second Military Medical University
2010;31(11):1244-1246
- CountryChina
- Language:Chinese
-
Abstract:
Abnormal activation of Wnt signaling pathway plays an important role in the development and progression of prostate cancer; androgen receptor (AR) is the key for the transformation of androgen-independent prostate cancer (AIPC), and AR signaling pathway is now the focus of prostate cancer research. Many signal pathways can affect AR signaling pathway; in this paper we review the Wnt signaling pathway, androgen receptor and their crosstalk in prostate cancer.
