Role of microRNA in development and progression of glioblastoma
10.3724/SP.J.1008.2011.00202
- Author:
Wei-Qing LI
1
Author Information
1. Department of Pathology
- Publication Type:Journal Article
- Keywords:
Cell proliferation;
Glioblastoma;
microRNAs;
Neoplasm metastasis;
Recurrence
- From:
Academic Journal of Second Military Medical University
2011;32(2):202-205
- CountryChina
- Language:Chinese
-
Abstract:
Glioblastoma, originating from glial cells, is the most commonly seen primary intracranial tumors in adults with extremely poor prognosis. miRNAs are a class of endogenous 18-26 nt non-coding RNAs playing important roles in a variety of biological processes. Recent studies have shown that miRNAs are closely associated with the development and progression of glioblastoma. In this paper, we summarize the regulatory roles of miRNAs in the progression of glioblastoma.