Multimodal antiemetic therapy for postoperative nausea and vomiting in patients receiving gynecological laparoscopic surgery
10.3724/SP.J.1008.2011.00447
- Author:
Zhi-Qiang LIU
1
Author Information
1. Dept. of Anesthesiology, Shanghai First Maternity and Infant Hospital
- Publication Type:Journal Article
- Keywords:
Gynecological Surgery;
Laparoscopy;
Postoperative nausea and vomiting;
Therapy
- From:
Academic Journal of Second Military Medical University
2011;32(4):447-449
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the clinical effect of Multimodal Antiemetic Therapy on Postoperative Nausea and Vomiting in Patients Undergone Gynecological Laparoscopic Surgery. Methods:Ninety gynecologic patients scheduled for laparoscopic Surgery were randomly divided into three groups with 30 cases each. Group A (Multimodal Group) received multimodal antiemetic therapy including the management of using TIVA with propofol for induction and maintenance of anesthesia, avoidance of volatile anesthetics, minimization of opioids, combination of using antiemetics ondansetron 4mg + dexamethasone 2.5mg + droperidol 1.25mg for preventing PONV.Group B (Combination Group)received combination antiemetics therapy. Group C(Control Group)didn't receive special interventions for PONV. Patient demographics,risk profiling,incidence of PONV and patient total satisfaction were observed and compared.Result: The preoperative expected risks of PONV in three groups were high. Group A and B were more effective than Group C in preventing PONV.Compared with Group B, Group A has a higher complete response rate and greater patient satisfaction. Conclusion:In Patients Undergone Gynecological Laparoscopic Surgery,evaluated to have a high risks of PONV preoperatively, multimodal antiemetic therapy has an effective prevention, also associated with a better clinical effect and greater patient satisfaction when compared with combination antiemetics therapy.
