Correlation analysis between sleep quality and mild cognitive impairment in elderly patients with type 2 diabetes mellitus
10.3724/SP.J.1008.2011.00404
- Author:
Lan LUO
1
Author Information
1. Department of Geriatrics
- Publication Type:Journal Article
- Keywords:
Aged;
Cognition disorders;
Sleep quality;
Type 2 diabetes mellitus
- From:
Academic Journal of Second Military Medical University
2011;32(4):404-408
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between sleep quality and mild cognitive impairment(MCI) in elderly patients with type 2 diabetes mellitus (T2DM). Methods We collected 97 elderly patients with type 2 diabetes mellitus and divided them into two groups: MCI group (DM-MIC) and normal cognition group (DM-NC group). All subjects were evaluated with cognition scores of Mini-mental state examination (MMSE), Montreal Cognitive Assessment (MOCA), Self-Rating Anxiety Scale(SAS), Center for Epidemiogical Studies Depression Scale (CES-D), Activity of daily living(ADL), Global Deterioration Scale(GDS), and Pittsburgh sleep quality index(PSQI). Independent t-test and Spearman's rank correlation analysis were performed. Results The hypnotic use in DM-MCI group was significantly more than that in DM-NC group (P = 0.046), and it had a negative correlation with the score of delayed recall, but not statistically significant(r= -0.277, P = 0.062). Significantly negative correlations were also found between the score of PSQI and MOCA (r= - 0.362), PSQI and attention(r= -0.319), PSQI and delayed recall (r= - 0.409), daytime dysfunction and MOCA (r= - 0.393), daytime dysfunction and abstraction (r= - 0.337), night sleep disorders and language (r= -0. 439), sleep efficiency and delayed recall (r = -0.325), and subjective sleep quality and delayed recall(r= -0.336) in DM-MCI group(P<0.05). Conclusion Sleep quality is correlated with some symptoms of mild cognitive impairment in elderly patients with T2DM.
