Angiotensin-(1-7) and its Mas receptor i an advance
10.3724/SP.J.1008.2011.00667
- Author:
Hui DU
1
Author Information
1. Department of Pharmacology
- Publication Type:Journal Article
- Keywords:
Angotensis;
Diseases;
Mas;
Sissijes
- From:
Academic Journal of Second Military Medical University
2011;32(6):667-672
- CountryChina
- Language:Chinese
-
Abstract:
In addilion to angiotensin II, angiotensin-(1-7) is another importarrt regulatory peplide of the renin-angiotensin system. It manly birds with a spediic receptor known as Mas, showing a vascijlar dilaSion and an ansi-proliferaSion effect, which counterbalances the effects of angiotersin H, mcluding VasoconstiiicSion, blood pressure mcrease, proliferaSion, \M\ne reteniion, etc. Recerrt studies demonstrate that angiotensin-(1-7) and its Mas receptor play aciiVe roles n local phyiiological process and showan protertive effect n many pathological condiSions.