Effect of hypoxia training on serum testosterone(T), corticosterone(C) and T/C value in rats
10.3724/SP.J.1008.2011.00710
- Author:
Xin-Fei WEN
1
Author Information
1. Department of Sports Biochemistry
- Publication Type:Journal Article
- Keywords:
Corticosterone;
Hypoxia training;
Testosterone
- From:
Academic Journal of Second Military Medical University
2011;32(7):710-712
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the changes of serum testosterone (T), corticosterone (C), and testosterone/ corticosterone (T/C) values in SD rats trained under different hypoxic conditions, so as to provide an experimental evidence for correct hypoxia training. Methods: A total of 60 SD rats (8-week-old) were randomly divided into 6 groups: normal control (C), normal exercise(E), 15% oxygen control (15C), 15% oxygen exercise (15E), 11% oxygen control(11C), and 11% oxygen exercise (11E) groups. The animals received treadmill running for exercise, and the levels of serum T and C were examined by ELISA. Results: (1) Testosterone level in group 11C was significantly lower than that in group C(P<0.05); testosterone level in group 11E was significantly lower than that in group E(P<0.01). (2) Corticosterone level in group E was significantly higher than that in group C(P<0.05); corticosterone levels in group 11E and 15E were significantly lower than that in group E(P<0.05). (3) The ratio of T/C in group 11C was significantly lower than that in group C(P<0.05). Conclusion: The 11% oxygen may cause negative effects on the T/C balance, but exercise may compensate the negative effect to some extent; the 15% oxygen causes no noticeable influence to T/C balance.
