Role of microRNA-mediated T lymphocyte activation in multiple sclerosis: Recent progress
10.3724/SP.J.1008.2011.00902
- Author:
Bing XIE
1
Author Information
1. Department of Internal Medicine Teaching
- Publication Type:Journal Article
- Keywords:
Autoimmune diseases;
MicroRNAs;
Multiple sclerosis;
T-lymphocytes
- From:
Academic Journal of Second Military Medical University
2011;32(8):902-905
- CountryChina
- Language:Chinese
-
Abstract:
Multiple sclerosis (MS) is an autoimmune disease involving the central nervous system. T lymphocytes are known to play an important role in maintaining the body's autoimmunity, and their dysfunction is the leading cause of MS. Recent study has found that microRNAs play a key role in T lymphocyte activation and pathogenesis of neurodegenerative diseases, and it has become a focus of study. This article reviews the roles of existing microRNA in T lymphocyte activation and in the pathogenesis of MS.
