Topological properties of genetic interaction network in yeast
- Author:
You-yi CUI
1
Author Information
1. Jilin Railway Vocational and Technology College
- Publication Type:Journal Article
- Keywords:
Genetic interaction;
Genome-scale;
Topology;
Yeasts
- From:
Academic Journal of Second Military Medical University
2011;32(10):1009-1012
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the topological properties of genomic-wide genetic interaction network in yea; Methods The topological properties of genomic-wide genetic interaction network in yeast were calculated by the graph theoi Results A power law fit the degree distribution well in the genomic-wide genetic interaction network in yeast, with t exponent approaching 3. TheNode's degree followed awide-tail distribution, with the average degree being 87. Two thirds the genes had genetic interaction via only one gene, and about one third of the genes had genetic interaction via only 2 gene The average clustering coefficient was 0. 047. Conclusion The gene function in yeast is usually multiple and the functioi interaction between genes is highly condensed.
