A novel balloon-expandable valved stents for transcatheter aortic valve implantation: Preparation and testing
10.3724/SP.J.1008.2013.00764
- Author:
Xiang CHEN
1
Author Information
1. Department of Cardiology, Changhai Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Aortic valve implantation;
Balloon-expandable stent;
Transcatheter;
Valved stent
- From:
Academic Journal of Second Military Medical University
2013;34(7):764-768
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the functions of a new balloon-expandable valved stent for transcatheter aortic valve implantation and the delivery system, so as to provide evidence for future animal study. Methods A new tube-like balloon- expandable valved stent was designed and made of cobalt-base alloys. Bovine pericardium was sutured by hand into the stent to prepare valved aortic stent, which was placed on the instrument to test the pulsating flow and fatigue property of prosthetic valve. The valved stent, which was compressed on a balloon catheter and pulled into a delivery sheath, was placed in the native aortic valve of isolated goat heart via the ascending aorta, and water was injected into the ascending aorta by a silicon tube to evaluate the competence of the prostheticheart valves. Results Plusating flow examination showed that the artificial valve opened and closed well, without noticeable reflow, and accorded with human physiology. The prosthetic heart valves also performed well in the testing of fatigue property. The valved stent could be stably placed in the native valves of goat heart by delivery sheath, and the prosthetic heart valves showed satisfactory function. Conclusion The aortic valved stent is wel-designed and has satisfactory function. It can be used for animal study of transcatheter aortic valve implantation.
