LDL cholesterol/HDL cholesterol ratio in newly diagnosed type 2 diabetic patients complicated with metabolic syndrome
10.3724/SP.J.1008.2014.01396
- Author:
Jue JIA
1
Author Information
1. The Affiliated Hospital of Jiangsu University
- Publication Type:Journal Article
- Keywords:
HDL cholesterol;
LDL cholesterol;
Metabolic syndrome;
Type 2 diabetes mellitus
- From:
Academic Journal of Second Military Medical University
2014;35(12):1396-1400
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change of low-density lipoprotein cholesterol (LDL-C) /high-density lipoprotein cholesterol (HDL-C) ratio in newly diagnosed patients with type 2 diabetes mellitus (T2DM) and metabolic syndrome (MS), and to discuss its relationship with the clinical parameters. Methods Totally 140 newly diagnosed T2DM patients were selected for this study, and they were divided into MS group (n=73) and non-MS group (n=67) according to the presence of MS; the normal control group included 73 participants (NC group). All participants underwent an oral glucose tolerance test (OGTT) and insulin releasing test; meanwhile, the blood glucose, insulin, blood lipid and other items were measured. The LDL-C/ HDL-C ratios of each group were calculated. Clinical parameters and LDL-C/HDL-C ratios were compared among different groups, and correlation analysis was made between LDL-C/HDL-C ratios and clinical indices. Furthermore, all participants were divided into three groups according to LDL-C/HDL-C levels and the prevalence rates of MS were compared. Results The LDL-C/HDL-C ratios of MS group (3.18±0. 85) and non-MS group (2. 61±0. 93) were significantly higher than that in NC group (2. 26 ±0. 70, P
