Impact of atrial fibrillation on early outcomes of patients underoin aortic valve replacement
10.3724/SP.J.1008.2014.00265
- Author:
Xi-Wu ZHAN
1
Author Information
1. Department of Cardiothoracic Surery, Chanhai Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Aortic valve replacement;
Atrial fibrillation;
Heart valve diseases;
Pronosis
- From:
Academic Journal of Second Military Medical University
2014;35(3):265-269
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the impact of atrial fibrillation (AF) on the early outcomes of patients underoin aortic valve replacement (AVR). Methods The clinical data of 961 adult patients who underwent AVR in Department of Cardiothoracic Surery, Chanhai Hospital between Jan. 2000 and Dec. 2011 were retrospectively analyzed. The patients with pre-operative AF were assined to AF roup (= 54) and the rest to non-AF roup (n = 907). Pre-, intra-, and postoperative findinswere compared to assess the impact of AF on early outcomes. Possible risk factors affectin the early mortality were identified usin loistic reression analysis. Results AF patients compared with non-AF patients had an elder age(P<0. 001), hiher NYHA functional classification ff (P = 0. 039), lower left ventricular ejection fraction (P = 0. 017), and hiher proportionof pulmonary hypertension (P < 0. 001). Accordinly, the postoperative early mortality, mechanical ventilation time, and incidences of low cardiac outputsyndrome, cardiac arrest/ventricular fibrillation, and acute renal failure were sinificantly hiher in the AF roup than those in the non-AF roup (P<0. 05). Loistic reression analysis showed that age, NYHA functional classification ff, AF and cardiopulmonary bypass time>120 min were independent risk factors for early mortality. Conclusion AF has a neative impact on the early outcomes of patients underoin AVR. AF patients have hiher pos-operative early mortality and more related complications compared with non-AF patients.
