Water soluble chemical constituents of Valeriana officinalis Linn. var. latiofolia Miq
10.3724/SP.J.1008.2014.00161
- Author:
Xian-Peng ZU
1
Author Information
1. Department of Natural Medicinal Chemistry, School of Pharmacy, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Chemical constituents;
Iridoids;
Latio folia Miq;
Lignin glycosides;
Monoterpenoid glucoside;
Valeriana officinalis Linn;
Var
- From:
Academic Journal of Second Military Medical University
2014;35(2):161-170
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the water soluble chemical constituents in the root of Valeriana officinalis Linn. var. latio folia Miq. and to identify their structures. Methods The water soluble chemical constituents were isolated and purified by macroporous resin Diaion HP-20, silica gel and Sephadex LH-20; the chemical structures of the components were determined by MS, 1D NMRand 2D NMR spectral analysis. Results and conclusion Thirteen constituents were isolated and identified from the root o f Valeriana officinalis Linn. var. latio folia, including Ganxinoside A (1), (-)-angelicoideno 1-2-0-β-D-glucopyranoside (2), (-)-angelicoidenol-2-0-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (3), 6-hydroxy-7-(hydroxymethyl)-4-methylenehexahydrocyclopenta [c] pyran-1 (3H)-one (4), kanokoside A (5), prinsepiol-4-O-β-D-glucopyranoside (6), (+)-pinoresinol-4-0-β-D-glucopyranoside (7), sinenoside I (8), lanicepsides A (9), (+)-1-hydroxypinoresinol-1-O-β-D-glucoside (10), (+)-pinoresinol-4, 4′-0-bisglucopyranoside (11), (+)-cycloolivil 6-O-β-D-glucopyranoside (12), and coniferin (13). All the 13 compounds are isolated from the root o f Valeriana officinalis Linn. var. latio folia Miq. for the first time.
