Non-viral vectors for targeted therapy of prostate cancer: Recent advance
10.3724/SP.J.1008.2015.00888
- Author:
Chong YAO
1
Author Information
1. Department of Pharmacy, Changhai Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Gene drug;
Non-viral vectors;
Prostatic neoplasms;
Targeted therapy
- From:
Academic Journal of Second Military Medical University
2015;36(8):888-892
- CountryChina
- Language:Chinese
-
Abstract:
The current therapies for treating prostate cancer, in many cases, also cause damage to normal tissues and organs at the same time when killing cancer cells. The recent development of targeted therapy to some extent, may be a good solution to this problem. As vectors in targeted therapy, viral vectors have strong immunogenicity, toxicity and other disadvantages, and non-viral vectors for targeted therapy of prostate cancer may overcome these drawbacks. This review summarized the recent application of cationic polymers, liposomes and polymeric chitosan as non-viral vectors of gene drug for targeted therapy of prostate cancer.
