Relationship between P2X7 receptor and bone metabolism: Recent progress
10.3724/SP.J.1008.2015.00767
- Author:
Zhe LI
1
Author Information
1. No. 73018 Troop of PLA
- Publication Type:Journal Article
- Keywords:
Bone metabolism;
Osteoblasts;
Osteoclasts;
P2X7 receptor
- From:
Academic Journal of Second Military Medical University
2015;36(7):767-770
- CountryChina
- Language:Chinese
-
Abstract:
P2X7 receptor, an ATP-gated ion channel, is widely found in various tissues and possesses multiple physiological functions. Recent reports have implicated expression of P2X7 receptor in both osteoblasts and osteoclasts, participating in both bone formation and resorption. This paper reviews the recent progresses on the influence of P2X7 receptor and its related pathways on bone metabolism.
