Neutrophil gelatinase-associated lipocalin and chronic kidney disease: A literature review
10.3724/SP.J.1008.2015.00304
- Author:
De-Chao XU
1
Author Information
1. Nephrology Institute of PLA, Changzheng Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Acute kidney injury;
Chronic kidney diseases;
Neutrophil gelatinase-associated lipocalin
- From:
Academic Journal of Second Military Medical University
2015;36(3):304-308
- CountryChina
- Language:Chinese
-
Abstract:
Chronic kidney disease (CKD) is a common disease with an estimated prevalence of 10%-16% in the general population. With high mortality and high risk of cardiovascular disease, CKD imposes substantial cost burden. Recent studies have shown that neutrophil gelatinase-associated lipocalin (NGAL) is tightly associated with CKD, suggesting that it has an important role in the diagnosis, treatment and monitoring of CKD. This paper reviewed the progress in the biological function, originality, structure, and role in CKD of NGAL.
