Effect of long-term alcohol consumption on morning blood pressure surge and its association with left ventricular hypertrophy in male hypertension patients
10.16781/j.0258-879x.2016.09.1115
- Author:
Xue-Qin JIA
1
Author Information
1. Department of Cardiology, Hospital of Bayannaoer
- Publication Type:Journal Article
- Keywords:
Alcohol drinking;
Ambulatory blood pressure monitoring;
Hypertension;
Left ventricular hypertrophy;
Morning blood pressure surge
- From:
Academic Journal of Second Military Medical University
2016;37(9):1115-1120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of long-term alcohol consumption on morning blood pressure surge (MBPS) and its association with left ventricular hypertrophy (LVH) in males with hypertension. Methods According to the findings of our questionnaire survey, 199 male patients with hypertension were divided into non-drinking, giving up drinking and mild, moderate and heavy drinking groups. The fasting plasma glucose (FPG), serum total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), heart rate (HR) and body mass index (BMI) were examined in all patients. The 24-hour ambulatory blood pressure monitoring and echocardiography were performed and the left ventricular mass index (LVMI) were calculated. The data were analyzed by using SPSS 10.0 software. Results The FPG, TC, TG, HDL,LDL HR, BMI and other parameters had no significant differences among the 5 groups (P>0. 05). The levels of 24- hour mean systolic blood pressure(24h SBP), daytime mean systolic blood pressure (dSBP) and nighttime mean systolic blood pressure(nSBP) in the non-drinking, giving up drinking and mild drinking groups were significantly lower than those in the moderate and heavy drinking groups (P<0. 05). The percentages of dipper systolic blood pressure and dipper diastolic blood pressurewere significantly higher, the MBPS value, incidence of increased MBPS, LVMI and incidence of LVH were significantly lower than those in the moderate and heavy drinking groups (P<0. 05). Theabove parameters were not significantly different among non-drinking, giving up drinking andmild drinking groups (P>0. 05). The average daily alcohol consumption was positively correlated with MBPS value andLVMI in the moderate and heavy drinking groups (P<0. 05). Conclusion Long-term moderate and heavy drinking can affect the circadian rhythm of blood pressure, and aggravate MBPS and LVH in males with hypertension. The MBPS and degree of LVH increase with the increase in alcohol consumption.
