Incidence and survival analysis of thyroid cancer among permanent residents in Yangpu district of Shanghai during 2002-2012
10.16781/j.0258-879x.2016.05.0569
- Author:
Qi SHEN
1
Author Information
1. Department of Geriatrics, Yangpu Hospital, Tongji University
- Publication Type:Journal Article
- Keywords:
Incidence;
Mortality;
Survival rate;
Thyroid neoplasms
- From:
Academic Journal of Second Military Medical University
2016;37(5):569-575
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the incidence and mortality of thyroid cancer among permanent residents in Yangpu district of Shanghai from January 2002 to December 2012, so as to evaluate the effect of surgical treatment on their survivals. Methods The data of thyroid cancer in permanent residents of Yangpu district were collected from the database of cancer registration and management system in Shanghai. Annual demographic data were obtained from Public Safety Department of Yangpu district. The temporal trend in the incidence and mortality of thyroid cancer was assessed using annual percent change (APC) model. Kaplan-Meier analysis with log-rank test was performed for survival analysis. Results A total of 1 488 cases with thyroid cancer were diagnosed from January 2002 to December 2012, accounting for 3.19% of the total patients with malignant diseases during the time in the area. Of those, 1 131 were females. The crude incidence rate was 19.45/105 in females, being significantly higher than 5.85/105 in males (P<0.05). The standardized incidence rate was 12.15/105 in females, also being significantly higher than 3.69/105 in males (P<0.05). The crude incidence of thyroid cancer increased significantly (APC=21.72%, P<0.05) from 2002 to 2012. A total of 146 cases died of thyroid cancer during this period, with the annual crude mortality being 1.79/105 in females, which was significantly higher than that in males (0.69/105, P<0.05). The standardized mortality rate was 0.35/105 in males and 0.85/105 in females (P<0.05). Both the incidence and mortality rates increased rapidly after 60 years old for both males and females. The 1- to 5- year survival rates in all cases were 97.20%, 96.70%, 96.10%, 95.40% and 94.80%, respectively. The rates in those receiving surgery were 99.20%, 98.90%, 98.70%, 98.30%, and 97.90%, which were significantly higher than those without surgery (91.9%, 90.60%, 89.00%, 88.00%, and 86.70%, respectively) (P<0.05 for each comparison). Conclusion The incidence of thyroid cancer is significantly higher than the mortality in permanent residents of Yangpu district in Shanghai. The incidence, rather than the mortality, is dramatically increased during 2002 and 2012. Both the incidence and mortality of thyroid cancer are significantly higher in females than in males, and surgical resection can significantly prolong the survival of thyroid cancer patients.
