CircRNA: Research progress and clinical applications
10.16781/j.0258-879x.2016.03.0330
- Author:
De-Pei KONG
1
Author Information
1. Department of Urology, Changhsi Hospital, Second Military Medicai University
- Publication Type:Journal Article
- Keywords:
Biogenesis;
Biological markers;
Circular RNA;
Disease;
Property
- From:
Academic Journal of Second Military Medical University
2016;37(3):330-335
- CountryChina
- Language:Chinese
-
Abstract:
Circular RNAs (circRNAs) are a species of RNAs with covalently closed loop structure and are widely expressed in eukaryocyte. Consisting of exons and/or introns, circRNAs are generated during the process of RNA splicing and are found to be relatively stable. evolutionally conserved and tissue/cell-specific. A few studies have indicated that circRNAs may participate in the RNARNA regulation network or RNA-protein complex formation and thus are involved in a diversity of diseases. including cancer. Here we reviewed the currently available outcomes and progress of researches concerning circRNAs and the potential relationship between diseases and circRNAs.
