Clinical outcome of fresh or frozen-thawed blastocyst transfer: A historic cohort study
10.16781/j.0258-879x.2017.07.0842
- Author:
Hui-rong YIN
1
Author Information
1. Reproductive Medicine Center, Changhai Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Blastula;
Cohort studies;
Embryo transfer;
Fresh;
Frozen-thawed;
Pregnancy outcome
- From:
Academic Journal of Second Military Medical University
2017;38(7):842-845
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relevant parameters and clinical outcome of frozen-thawed blastocyst transfer compared with fresh blastocyst transfer. Methods A historic cohort study was conducted to analyze the blastocyst implantation rate and clinical pregnancy rate of 61 patients receiving fresh blastocyst transfer and 372 receiving frozen-thawed blastocyst transfer from Mar. 2015 to Dec. 2016 in Changhai Hospital of Second Military Medical University. And then the clinical outcomes of day five (n=308) or day six (n=64) embryo were analyzed in the frozen-thawed blastocyst transfer group. Results There was no significant difference in age or number of the transferred blastocysts between the two groups. Blastocyst implantation rate in frozen-thawed blastocyst transfer group was significantly higher than that in fresh blastocyst transfer group (40.2% vs 29.6%, P=0.036), while no significant difference was found in clinical pregnancy rate between the two groups (57.8% vs 47.5%, P=0.134). Blastocyst implantation rate and clinical pregnancy rate of day five embryo were significantly higher than those of day six (42.3% vs 30.1%, P=0.016, and 60.7% vs 43.8%, P=0.012, respectively). Conclusion The pregnancy outcome of frozen-thawed blastocyst transfer is better compared with fresh blastocyst transfer, especially when transferring on day five.
