Role of protein phosphatase in regulating antiviral innate immune response
10.16781/j.0258-879x.2017.06.0769
- Author:
Yun-Kai ZHANG
1
Author Information
1. National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Antiviral responses;
Interferon type I;
Natural immunity;
Protein phosphatase
- From:
Academic Journal of Second Military Medical University
2017;38(6):769-773
- CountryChina
- Language:Chinese
-
Abstract:
Protein phosphatases play critical roles in regulating cell division, cell apoptosis, and cell cycle in eukaryotic cells, participating in numerous signal transduction processes and exerting a large amount of significant biological functions. A variety of protein phosphatases are identified to maintian the phosphorylation level of key proteins with a moderate level in the antiviral innate immune response to virus infectioa In this paper, we reviewed the roles of serine/threonine protein phosphatases, tyrosine protein phosphatases, and lipid phosphatases in regulating antiviral innate immune responses.
