Application and research progress of electret in transdermal drug delivery
10.16781/j.0258-879x.2018.03.0308
- Author:
Li-Li CUI
1
Author Information
1. Department of Inorganic Chemistry, School of Pharmacy, Navy Medical University, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Biological effect;
Electret;
Electrostatic field;
Microcurrent;
Transdermal drug delivery
- From:
Academic Journal of Second Military Medical University
2018;39(3):308-313
- CountryChina
- Language:Chinese
-
Abstract:
Transdermal drug delivery has become one of the research focuses in pharmaceutical formulations due to its potential advantages. In order to overcome the natural barrier function of the skin, several physical, chemical and pharmaceutical enhancement strategies have been developed to promote the transdermal permeation and adsorption of drugs. Electret is a kind of functional dielectric material with permanent electric polarization state. The electrostatic filed and microcurrent produced by electret can be used as physical permeation enhancer to improve the transdermal drug delivery. In this article, we reviewed the mechanism, influencing factors and current research progress of electret as one of the physical enhancing permeation strategies.
