Risk factors and clinical features of ischemic complication in endovascular treatment of unruptured intracranial aneurysm
10.16781/j.0258-879x.2018.01.0050
- Author:
Li LI
1
Author Information
1. Department of Neurosurgery, Changhai Hospital, Second Military Medical University
- Publication Type:Journal Article
- Keywords:
Complication;
Endovascular treatment;
Intracranial aneurysm;
Risk factor
- From:
Academic Journal of Second Military Medical University
2018;39(1):50-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyzed the risk factors and clinical features of ischemic complication (IC) in the endovascular treatment (EVT) of unruptured intracranial aneurysm (UIA), so as to reduce the incidence of IC. Methods We retrospectively analyzed the clinical and imaging features of 1 232 patients with UIA, who received EVT in Changhai Hospital, Second Military Medical University from Jan. 2010 to Feb. 2017. Univariate and multivariate analyses were performed to analyze the risk factors of IC. Results IC occurred in 34 (2.8%) of 1 232 patients with UIA in this study, including 16 cases of acute stent thrombus formation, 3 cases of transient ischemic attack, and 15 cases of postoperative cerebral infarction. Univariate analysis showed that hypertension (P＝0.002), smoking (P＝0.050), and aneurysm maximum diameter10 mm (P＝0.005) were associated with IC. Multivariate analysis showed that hypertension (OR＝ 3.192, P＝0.003), smoking (OR＝2.956, P＝0.022) and aneurysm maximum diameter10 mm (OR＝2.915, P＝0.004) were independent risk factors of IC. The permanent disability rate and mortality rate of IC were 8.8% (3/34) and 2.9% (1/34), respectively. Conclusion Hypertension, smoking and aneurysm maximum diameter10 mm are independent risk factors of IC in the EVT of UIA.
