Advance on anti-tumor activities of sinoporphyrin sodium
10.16781/j.0258-879x.2018.11.1259
- Author:
Bing ZHU
1
Author Information
1. Department of Pharmacy, Changhai Hospital, Navy Medical University (Second Military Medical University)
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Photodynamic therapy;
Sinoporphyrin sodium;
Sonodynamic therapy
- From:
Academic Journal of Second Military Medical University
2018;39(11):1259-1264
- CountryChina
- Language:Chinese
-
Abstract:
Photodynamic therapy (PDT) is a new oncotherapy method. Photosensitizer and matched-light are the key elements of PDT. As a next generation photosensitizers of high purity, sinoporphyrin sodium (DVDMS) has the characteristics of clear structure and high content, low effective dose, short time avoiding light after treatment and good safety. Due to the discovery of ultrasonic sensitivity of DVDMS, great progresses have been made on the research and application of DVDMS-mediated sonodynamic therapy. Research suggests that DVDMS has potentials to be used for anti-tumor, anti-bacterial, treatment of psoriasis, development of therapeutic diagnostic reagents and so on. This review sums up the anti-tumor activities and mechanisms of DVDMS.
