The relationship between the serum lactate level and in-hospital mortality after decompressive craniectomy in traumatic brain Injury.
10.17085/apm.2015.10.3.192
- Author:
Wol Seon JUNG
1
;
Dongchul LEE
;
Young Jin CHANG
;
Chun Kon PARK
;
Youn Yi JO
Author Information
1. Department of Anesthesiology and Pain Medicine, Gachon University Gil Medical Center, Incheon, Korea. endless37@gilhospital.com
- Publication Type:Original Article
- Keywords:
Mortality;
Serum lactate;
Traumatic brain injury
- MeSH:
Brain Injuries*;
Decompressive Craniectomy*;
Demography;
Hospital Mortality*;
Humans;
Intracranial Pressure;
Ischemia;
Lactic Acid*;
Medical Records;
Mortality;
Retrospective Studies;
ROC Curve;
Survivors
- From:Anesthesia and Pain Medicine
2015;10(3):192-195
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The patients with traumatic brain injury showed ischemia due to increased intracranial pressure. This study evaluated the relationship of pre-anesthetic serum lactate level with in-hospital mortality. METHODS: The archived medical records of 121 patients were retrospectively reviewed. Demographics and preoperative serum lactate level were analyzed. RESULTS: Of the 121 patients, 32 patients expired in the hospital after decompressive craniectomy. Preoperative serum lactate levels were 3.2 +/- 2.2 mmol/L in the survivors and 5.4 +/- 3.0 mmol/L in the dead (P = 0.001), and the receiver operating characteristic curve revealed that a cut off value of 3.60 mmol/L was reasonable for predicting mortality. CONCLUSIONS: Preoperative serum lactate level is highly correlated with in-hospital mortality after decompressive craniectomy in traumatic brain injury.