Research progress of matrix metalloproteinases in cerebrovascular diseases
10.16781/j.0258-879x.2020.07.0751
- VernacularTitle: 基质金属蛋白酶在脑血管疾病中的研究进展
- Author:
Hai-Shuang TANG
1
Author Information
1. Department of Neurosurgery, Changhai Hospital, Naval Medical University (Second Military Medical University)
- Publication Type:Journal Article
- Keywords:
Atherosclerosis;
Cerebrovascular disorders;
Intracranial aneurysm;
Matrix metalloproteinases;
Stroke
- From:
Academic Journal of Second Military Medical University
2020;41(7):876-879
- CountryChina
- Language:Chinese
-
Abstract:
Cerebrovascular diseases such as intracranial atherosclerosis, intracranial aneurysm and ischemic stroke have become the important causes of death and disability. The structural and functional changes of cerebrovascular, which are caused by various pathogenic factors, are the common pathophysiological basis of cerebrovascular diseases. At present, the etiology of cerebrovascular diseases has not been clarified. Growing evidence suggests that matrix metalloproteinases play an important role in the occurrence and development of cerebrovascular diseases. Blocking or inhibiting the expression of matrix metalloproteinases provides a new theoretical basis for non-invasive treatment of cerebrovascular diseases. This review discusses the relationship between matrix metalloproteinases and cerebrovascular diseases.
